"The cause of gastrointestinal symptoms after drinking dairy products is infant lactose intolerance." Do you think so? Indeed, such misunderstandings may be deeply rooted in the heart, but in fact, it is probably a protein contained in milk - —The effect of β-casein behind.
In 2016, Professor Sun Jianqin from Huadong Hospital affiliated to Fudan University published the first research results on Chinese people's symptoms of "lactose intolerance" caused by A 1 protein in milk. In 2017, a clinical trial of 600 Han Chinese adults who were self-diagnosed as lactose intolerance, led by Professor Yang Yuexin, chairman of the Chinese Nutrition Society, was released in Beijing. It is worth mentioning that the double-blind, random, cross-over, and peer-reviewed research results of Chinese experts have been published by the British Journal of Nutrition.
Also in 2017, with the support of the New Zealand government, David Cameron-Smith, a professor at the Riggins Institute at the University of Auckland in New Zealand, also published independent research results with similar results. After the research was released, more than 100 scientists in related fields have contacted David Cam eron-Smith to discuss the results. The scientists who completed the “Three Cities” study in China are international experts. These prestigious scientists have been deeply involved in the nutrition research of many important children and adults over the past decade. Every scientific research paper in an authoritative journal must be reviewed and reviewed by peers before it can be published. The whole process is very difficult and long. Therefore, once the paper is successfully published in a scientific journal, it indicates that it has passed various important reviews.
Studies have confirmed that some people who are self diagnosed as lactose intolerance may have symptoms associated with A 1-β casein after ingestion of conventional milk, rather than lactose itself. Today, let's talk about the need to update the knowledge about beta-casein in milk.
Is the milk what food has protein still classified?
Milk is an indispensable necessity in people's daily life, because its nutritional value plays an important role in the diet structure of modern people. However, it has to be acknowledged that lactose intolerance, which is accompanied by milk, also plagues many milk lovers. For them, "love you but dare not approach you" is their confession of milk.
Milk contains a protein called beta-casein, which is the main protein in milk. Due to genetic polymorphism (from mutations), two major variants, the A 1 and A 2 type β-casein, have emerged. According to scientists' research, the A 1 type produces a protein fragment called BCM-7 during digestion, while the A 2 type does not, if any, be negligible. BCM-7 is an exorphin or peptide (protein fragment) that exhibits different symptoms in combination with systemic cells or tissues.
The difference in the type of β-casein contained in milk has been discovered by scientists decades ago. Studies on A 1 and A 2 types of β-casein and BCM-7 have been conducted in international academic circles. . In fact, over the past two decades, more than 140 independent scientific studies have been published in international peer review journals. Governments and research institutions, including the New Zealand government, Purdue University, Shanghai Jiaotong University, and the University of Auckland's Riggins Institute, are all involved. Although decades have been a short time for a scientific research, the understanding of A 1 and A 2 types of proteins has been continuously refreshed by the research of many scientists around the world.
The latest study entitled "Effects of milk beta-casein variability on the symptoms of milk intolerance in Chinese adults: a multicenter randomized controlled trial" was published in the authoritative journal Nutritional Journal, an independent and peer-reviewed journal in the UK. This clinical trial covered 600 Chinese Han adults who were self-diagnosed as lactose intolerance. The volunteers who participated in the study were selected from 1,200 people who were diagnosed with lactose intolerance and had stomach upset after drinking traditional milk. 200 people were selected from Beijing, Shanghai and Guangzhou. All of the volunteers who participated in the study were not among the people who used to drink milk for a long time (they had not consumed milk for at least 4 weeks before the study), and they all diagnosed themselves as lactose intolerance. This trial follows the double-blind, random, and crossover principle and lasts for several months.
The experts who participated in the research came from Beijing, Shanghai and Guangzhou. Prof. Yang Yuexin, Researcher of Nutrition and Health Center of China Center for Disease Control and Prevention, Professor Yang Yuexin, Director of China Nutrition Society, Dr. He Mei, Research Fellow, Beijing Institute of Nutritional Sources, Fudan University Professor Sun Jianqin, director of the Nutrition Department of the affiliated Huadong Hospital, and Professor Jiang Zhuoqin, director of the Department of Nutrition, School of Public Health, Zhongshan Medical University, led the study.
The experimental results show that drinking milk containing only A 2-β casein can reduce or attenuate acute gastrointestinal symptoms compared to traditional milk containing both A 1 and A 2 proteins, while traditional milk containing A 1-β casein It reduces the activity of lactase and increases gastrointestinal discomfort compared with milk containing only A 2-β casein. Moreover, those A 1 proteins were converted to A 2 protein milk drinkers, and the problems of gastrointestinal discomfort such as diarrhea and flatulence were improved. Even in the cognitive function test, the subjects were in the drinking A 2 stage compared with the test results of drinking A 1 . The response is more agile and the accuracy is improved.
Lactose free formula for babies is no longer a scapegoat
Studies have shown that A 2 protein is the most natural source of milk protein. At first, all cows and mammals produced milk containing all A 2 protein, while A 1 protein was caused by genetic mutations in European cows about 5,000 years ago. Appeared after the mutation. Therefore, the A 2 protein is a natural protein that is more intimate with the human body.
Because of its nutritional value, milk occupies an important position in the diet structure of modern people, and many Chinese people have little or no milk because they think that lactose intolerance is long after drinking milk. This study further reveals other causes of Chinese milk intolerance symptoms through a sample size of up to 600 people. This is of great significance to the Chinese people's nutritional diet.
Robert Elliott, a former professor of pediatric medicine at the University of Auckland, also commented on the findings of Chinese experts in 2017: “Many Chinese adults often suffer from nauseous intestinal discomfort even if they only drink a glass of milk. People usually blame this on the human body. Indigestion of lactose in milk. In this study of many Chinese, volunteers have suffered from the inability to accept milk. The researchers provided the volunteers with the same amount of lactose in milk, but the casein type was not The same is true. It is clear that A 1-β casein is the cause of discomfort after drinking milk, not just lactose itself. This means that A 1-β casein will stimulate the intestinal tract to some extent. digestion."
Knowing the protein in dairy products may help countless Chinese who want to drink dairy products to ease the discomfort during dairy products digestion and regain the delicious and health benefits of dairy products . The release of the latest research results may be the first step to break this misunderstanding, which may also change people's lives.